Summary

Name CELF6
Full Name CUGBP Elav-like family member 6
Synonyms CELF-6, Bruno-like protein 6, CUG-BP- and ETR-3-like factor 6, RNA-binding protein BRUNOL-6 | BRUNOL6
Primary ID Q96J87
Links - -
Type protein
Relations 2
Function RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer (MSE)-dependent manner. Promotes also exon exclusion of INSR pre-mRNA.

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Relations

Regulator Mechanism target score
+ up-regulates quantity by stabilization img/direct-activation.png post transcriptional regulation CDKN1A 0.2
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity by destabilization img/direct_inhibition.png ubiquitination CELF6 0.2
Publications: 1 Organism: Homo Sapiens