Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-271651 |
|
|
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
17468759 |
Here we report that PDLIM2 negatively regulated NF-kappaB activity, acting as a nuclear ubiquitin E3 ligase targeting the p65 subunit of NF-kappaB. PDLIM2 bound to p65 and promoted p65 polyubiquitination. |
|