4.0
Summary
| Name |  RITA1
|
| Full Name | RBPJ-interacting and tubulin-associated protein 1 |
| Synonyms | RBPJ-interacting and tubulin-associated protein | C12orf52, RITA |
| Primary ID | Q96K30 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis. |
binding