Summary

Name PRICKLE1
Full Name Prickle-like protein 1
Synonyms REST/NRSF-interacting LIM domain protein 1 | RILP
Primary ID Q96MT3
Links - -
Type protein
Relations 1
Function Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure. Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalate between neighboring cells, leading to convergence toward the mediolateral axis and extension along the anteroposterior axis. Necessary for nuclear localization of REST. May serve as nuclear receptor.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png phosphorylation PRICKLE1 0.299
Publications: 1 Organism: In Vitro