Relation Results

Summary

Name JAKMIP1
Full Name Janus kinase and microtubule-interacting protein 1
Synonyms GABA-B receptor-binding protein, Multiple alpha-helices and RNA-linker protein 1, Marlin-1 | GABABRBP, JAMIP1, MARLIN1
Primary ID Q96N16
Links - -
Type protein
Relations 3
Function Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and ...
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Type: Score: Layout: SPV 
0.20.20.526KIF5BJAKMIP1TUBBGABBR1

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Relations
Regulator
Mechanism
target
score ℹ
+ KIF5Bup-regulates activity img/direct-activation.png relocalization JAKMIP1 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-260989 Mus musculus
pmid sentence
Marlin-1 is associated with kinesin-I and suggest that the movement of Marlin-1 is mediated by plus end microtubuledependent molecular motors
Publications: 1 Organism: Mus Musculus
+ JAKMIP1up-regulates quantity by stabilization img/direct-activation.png binding TUBB 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-260987 Homo sapiens JURKAT Cell
pmid sentence
In Jamip1, the N-terminal region mediates the association with microtubules, when highly expressed, N-ter drastically affects the organization of microtubules that appear to be bundled, stabilized against the depolymerizing effect of nocodazole, and enriched in acetylated tubulin.
Publications: 1 Organism: Homo Sapiens
+ JAKMIP1up-regulates quantity img/indirect-activation.png GABBR1 0.526
Identifier Residue Sequence Organism Cell Line
SIGNOR-260988 Chlorocebus aethiops COS Cell
pmid sentence
Reduction in the Marlin-1 protein levels interferes with the translation, assembly, or stability of GABAB receptors during the maturation of cortical neurons.
Publications: 1 Organism: Chlorocebus Aethiops
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