| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281545 |
|
|
Homo sapiens |
ACH-2 Cell |
| pmid |
sentence |
| 33886554 |
Using this threshold G protein coupling was detected for 22 of the 48 receptors and 48 of the 240 pairings in our sample (Fig 3; S1 File). We detected constitutive coupling of 18 receptors to Gi1, 8 receptors to Gs, 6 receptors to Gq, 7 receptors to G13, and 9 receptors to G15. Of the 22 profiled receptors 11 are annotated for G protein coupling in the IUPHAR Guide to Pharmacology (GtoPdb), and within this set there was excellent agreement between our results and annotated coupling |
|