Summary

Name ADCY10
Full Name Adenylate cyclase type 10
Synonyms AH-related protein, Adenylate cyclase homolog, Germ cell soluble adenylyl cyclase, hsAC, sAC, Testicular soluble adenylyl cyclase | SAC
Primary ID Q96PN6
Links - -
Type protein
Relations 3
Pathways Macropinocytosis
Function Catalyzes the formation of the signaling molecule cAMP (PubMed:12609998, PubMed:15659711, PubMed:24616449, PubMed:25040695, PubMed:24567411). May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels (PubMed:15659711, PubMed:17591988). Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization (By similarity). Involved in ciliary beat regulation (PubMed:17591988).

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Relations

Regulator Mechanism target score ℹ
+ NF1up-regulates img/indirect-activation.png ADCY10 0.276
Publications: 1 Organism: Homo Sapiens
+ ADCY10up-regulates quantity img/direct-activation.png chemical modification 3',5'-cyclic AMP 0.8
Publications: 1 Organism: Homo Sapiens
+ hydrogencarbonateup-regulates activity img/direct-activation.png chemical activation ADCY10 0.8
Publications: 1 Organism: Homo Sapiens