Summary

Name PANX1
Full Name Pannexin-1
Synonyms | MRS1
Primary ID Q96RD7
Links - -
Type protein
Relations 1
Function Structural component of the gap junctions and the hemichannels involved in the ATP release and nucleotide permeation (PubMed:16908669, PubMed:20829356, PubMed:30918116). May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis (PubMed:16908669). Plays a critical role in oogenesis (PubMed:30918116). {ECO:0000269|PubMed:16908669, ECO:0000269|PubMed:20829356, ECO:0000269|PubMed:30918116}.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png phosphorylation PANX1 0.388
Publications: 1 Organism: Homo Sapiens