Relation Results

Name	PNKP View Modifications
Full Name	Bifunctional polynucleotide phosphatase/kinase
Synonyms	DNA 5'-kinase/3'-phosphatase, Polynucleotide kinase-3'-phosphatase
Primary ID	Q96T60
Links	- -
Type	protein
Relations	4
Function	Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. Through its two catalytic activities, PNK ensures that DNA termini are compatible with extension and ligation by either removing 3'-phosphates from, or by phosphorylating 5'-hydroxyl groups on, the ribose sugar of the DNA backbone.