Summary

Name CDC5L
Full Name Cell division cycle 5-like protein
Synonyms Cdc5-like protein, Pombe cdc5-related protein | KIAA0432, PCDC5RP
Primary ID Q99459
Links - -
Type protein
Relations 3
Function DNA-binding protein involved in cell cycle control. May act as a transcription activator. Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes (PubMed:11991638, PubMed:20176811, PubMed:28502770, PubMed:28076346, PubMed:29361316, PubMed:29360106, PubMed:29301961, PubMed:30728453, PubMed:30705154). Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR) (PubMed:20176811).

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding HNRNPM 0.618
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by stabilization img/direct-activation.png binding CDC5L 0.443
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding PRP19-CDC5L 0.907
Publications: 1 Organism: Homo Sapiens