Summary

Name MGLL
Full Name Monoglyceride lipase
Synonyms MGL, HU-K5, Lysophospholipase homolog, Lysophospholipase-like, Monoacylglycerol lipase, MAGL |
Primary ID Q99685
Links - -
Type protein
Relations 2
Function Converts monoacylglycerides to free fatty acids and glycerol (PubMed:19029917, PubMed:20079333, PubMed:21049984, PubMed:22969151, PubMed:24368842). Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (PubMed:19029917, PubMed:20079333, PubMed:21049984, PubMed:22969151, PubMed:24368842). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth (PubMed:20079333).

Viewer

Relations

Regulator Mechanism target score
+ down-regulates quantity by destabilization img/direct_inhibition.png binding MGLL 0.2
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/indirect_inhibition.png Proliferation 0.7
Publications: 1 Organism: Homo Sapiens