Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-273842 |
Ser84 |
PNQWRYSsPWTKPQP |
Homo sapiens |
NUGC-3 Cell |
pmid |
sentence |
33069758 |
Site-directed mutagenesis and immunoprecipitation experiments revealed that RSK2 phosphorylated VGLL1 at S84 in the presence of TGF-β. Mutation of VGLL1 at S84 suppressed VGLL1-TEAD4 binding and the subsequent transcriptional activation of matrix metalloprotease 9 (MMP9). |
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