Summary

Name PAIP2
Full Name Polyadenylate-binding protein-interacting protein 2
Synonyms PABP-interacting protein 2, PAIP-2, Poly(A | PAIP2A
Primary ID Q9BPZ3
Links - -
Type protein
Relations 1
Function Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization. {ECO:0000269|PubMed:11172725}.

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Relations

Regulator Mechanism target score
+ down-regulates quantity by destabilization img/direct_inhibition.png polyubiquitination PAIP2 0.459
Publications: 1 Organism: Homo Sapiens