Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-266103 |
|
|
Mus musculus |
NIH-3T3 Cell |
pmid |
sentence |
24165133 |
Kindlin binds migfilin tandem LIM domains and regulates migfilin focal adhesion localization and recruitment dynamics. Two integrin-binding proteins present in FAs, kindlin-1 and kindlin-2, are important for integrin activation, FA formation, and signaling. By binding filamin, migfilin provides a link between kindlin and the actin cytoskeleton. |
|