Summary

Name CENPK
Full Name Centromere protein K
Synonyms CENP-K, Interphase centromere complex protein 37, Protein AF-5alpha, p33 | ICEN37
Primary ID Q9BS16
Links - -
Type protein
Relations 2
Function Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Acts in coordination with KNL1 to recruit the NDC80 complex to the outer kinetochore.

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding CCAN complex 0.714
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding SOX6 0.487
Publications: 1 Organism: Cricetulus Griseus