Summary

Name CCM2
Full Name Cerebral cavernous malformations 2 protein
Synonyms Malcavernin | C7orf22
Primary ID Q9BSQ5
Links - -
Type protein
Relations 1
Function Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions (By similarity). May function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock (By similarity).

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png phosphorylation CCM2 0.515
Publications: 1 Organism: Homo Sapiens