+ |
STK25 | up-regulates
phosphorylation
|
CCM2 |
0.515 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-263144 |
Ser384 |
GRGIITDsFGRHRRA |
Homo sapiens |
Medulloblastoma Cell |
pmid |
sentence |
22782892 |
CCM2 can be phosphorylated by STK25, and the kinase activity of STK25 is required for death signaling. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
STK25 |
phosphorylation
|
PDCD10 |
0.791 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-185388 |
Ser39 |
ELERVNLsAAQTLRA |
Homo sapiens |
|
pmid |
sentence |
19370760 |
Stk25 phosphorylates ccm3 at serine 39 and threonine 43 |
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-185392 |
Thr43 |
VNLSAAQtLRAAFIK |
Homo sapiens |
|
pmid |
sentence |
19370760 |
Stk25 phosphorylates ccm3 at serine 39 and threonine 43 |
|
Publications: |
2 |
Organism: |
Homo Sapiens |
+ |
PTPN13 | down-regulates activity
dephosphorylation
|
STK25 |
0.431 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-248711 |
|
|
Homo sapiens |
|
pmid |
sentence |
17657516 |
To investigate dephosphorylation of CCM3 by FAP-1, phosphorylated GST-CCM3 was incubated with cdFAP-1, and reactions were analyzed by autoradiography. Again, GST-STK25 phosphorylated GST-CCM3 and possessed autophosphorylation activity. cdFAP-1 of 0.005 U were sufficient to dephosphorylate GST-CCM3 as well as the kinase GST-STK25.|More recently, the Golgi matrix protein GM130 was shown to function as a scaffold protein for STK25 and to activate STK25 through stimulation of autophosphorylation. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |