Summary

Name SOX7
Full Name Transcription factor SOX-7
Synonyms SOX7_HUMAN |
Primary ID Q9BT81
Links - -
Type protein
Relations 1
Function Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors (By similarity). May be required for the survival of both hematopoietic and endothelial precursors during specification (By similarity). Competes with GATA4 for binding and activation of the FGF3 promoter (By similarity). Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'-AACAAT-3'.

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Relations

Regulator Mechanism target score ℹ
+ CHD8down-regulates quantity img/direct_inhibition.png transcriptional regulation SOX7 0.2
Publications: 1 Organism: Mus Musculus