Relation Results

Summary

Name MLST8
Full Name Target of rapamycin complex subunit LST8
Synonyms TORC subunit LST8, G protein beta subunit-like, Gable, Protein GbetaL, Mammalian lethal with SEC13 protein 8, mLST8 | GBL, LST8
Primary ID Q9BVC4
Links - -
Type protein
Relations 2
Function Subunit of both mTORC1 and mTORC2, which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in respo ...
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Type: Score: Layout: SPV 
0.8860.833MLST8mTORC1mTORC2

Relations

Regulator
Mechanism
target
score
+ form complex img/form-complex.png binding mTORC1 0.886
Identifier Residue Sequence Organism Cell Line
SIGNOR-205609 Homo sapiens
pmid sentence
Depending on their binding partners and sensitivities to rapamycin, mtor resides in at least two distinct complexes, termed mtor complex 1 (mtorc1, containing raptor, fkbp12, pras40 and mlst8) and mtor complex 2 (mtorc2, containing rictor, sin1, protor and mlst8)
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding mTORC2 0.833
Identifier Residue Sequence Organism Cell Line
SIGNOR-205612 Homo sapiens
pmid sentence
Depending on their binding partners and sensitivities to rapamycin, mtor resides in at least two distinct complexes, termed mtor complex 1 (mtorc1, containing raptor, fkbp12, pras40 and mlst8) and mtor complex 2 (mtorc2, containing rictor, sin1, protor and mlst8)
Publications: 1 Organism: Homo Sapiens
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