Summary

Name BRIP1
Full Name Fanconi anemia group J protein
Synonyms Protein FACJ, ATP-dependent RNA helicase BRIP1, BRCA1-associated C-terminal helicase 1, BRCA1-interacting protein C-terminal helicase 1, BRCA1-interacting protein 1 | BACH1, FANCJ
Primary ID Q9BX63
Links - -
Type protein
Relations 4
Function DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1.

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding BRCA1-B complex 0.661
Publications: 1
+ up-regulates activity img/direct-activation.png binding BRCA1 0.787
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by stabilization img/direct-activation.png binding BLM 0.642
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding BRIP1 0.684
Publications: 1 Organism: Homo Sapiens