| + |
PEG3 | down-regulates quantity by repression 
transcriptional regulation
|
NT5C1A |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-282737 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 23078764 |
Initially, we identified and characterized a subset of PEG3’s target genes and their DNA-binding motif. PEG3 was also shown to regulate the expression of Pgm2l1 through the binding of the identified motif. A gene expression survey of the validated PEG3 bound genes (from Figure 1) demonstrated multiple responses in which gene expression was either reduced (Grb10, Mapk14, Nt5c1a, Ppargc1b, Setd1a, Syap1, Wnt9a), increased (Dusp1, Pgm2l1), or remained the same (Aebp2, Eml2, Ndufs8, Sdhb). |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-282738 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 23078764 |
Initially, we identified and characterized a subset of PEG3’s target genes and their DNA-binding motif. PEG3 was also shown to regulate the expression of Pgm2l1 through the binding of the identified motif. A gene expression survey of the validated PEG3 bound genes (from Figure 1) demonstrated multiple responses in which gene expression was either reduced (Grb10, Mapk14, Nt5c1a, Ppargc1b, Setd1a, Syap1, Wnt9a), increased (Dusp1, Pgm2l1), or remained the same (Aebp2, Eml2, Ndufs8, Sdhb). |
|
| Publications: |
2 |
Organism: |
Mus Musculus |
| Tissue: |
Brain |
4.0
NT5C1A
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