Summary

Name GPR62
Full Name G protein-coupled receptor 62
Synonyms G protein-coupled receptor GPCR8, hGPCR8, G protein-coupled receptor KPG_005 |
Primary ID Q9BZJ7
Links - -
Type protein
Relations 3
Function Orphan G protein-coupled receptor. Constitutively activates the G(q/11)/inositol phosphate and the G(s)-alpha/cAMP signaling pathways (PubMed:28827538). Has spontaneous activity for beta-arrestin recruitment (PubMed:28827538). Shows a reciprocal modulation of signaling functions with the melatonin receptor MTNR1B most likely through receptor heteromerization (PubMed:28827538). {ECO:0000269|PubMed:28827538}.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding GNAS
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAI1
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNA15
Publications: 1 Organism: Homo Sapiens