Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-236978 |
Ser99 |
QERVRKTsLDLRREI |
Mus musculus |
C2C12 Cell, Myoblast |
pmid |
sentence |
21737686 |
In vitro and in vivo studies confirmed that akt phosphorylates ankrd2 at ser-99. moreover, the forced expression of a phosphorylation-defective mutant form of ankrd2 in c2c12 myoblasts promoted a faster differentiation program, implicating akt-dependent phosphorylation at ser-99 in the negative regulation of myogenesis in response to stress conditions. |
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