3.0
Summary
| Name |  COA1
|
| Full Name | Cytochrome c oxidase assembly factor 1 homolog |
| Synonyms | Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 15 kDa | C7orf44, MITRAC15 |
| Primary ID | Q9GZY4 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for assembly of mitochondrial respiratory chain complex I and complex IV (PubMed:23260140). As part of the MCIA complex, required for efficient assembly of the mitochondrial complex I (PubMed:32320651). |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | COA1 | form complex 
binding
|
MITRAC complex | 0.393 |
| Publications: | 1 | Organism: | Homo Sapiens | |