Summary

Name ING2
Full Name Inhibitor of growth protein 2
Synonyms Inhibitor of growth 1-like protein, ING1Lp, p32, p33ING2 | ING1L
Primary ID Q9H160
Links - -
Type protein
Relations 2
Function Seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides (PtdInsPs).

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Relations

Regulator Mechanism target score
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation MMP13 0.4
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation AFP 0.2
Publications: 1 Organism: Homo Sapiens