3.0
Summary
| Name |  TRIOBPView Modifications |
| Full Name | TRIO and F-actin-binding protein |
| Synonyms | Protein Tara, Trio-associated repeat on actin | KIAA1662, TARA |
| Primary ID | Q9H2D6 |
| Links |  -  -  |
| Type | protein |
| Relations | 4 |
| Function | May regulate actin cytoskeletal organization, cell spreading and cell contraction by directly binding and stabilizing filamentous F-actin. The localized formation of TARA and TRIO complexes coordinates the amount of F-actin present in stress fibers. May also serve as a linker protein to recruit proteins required for F-actin formation and turnover. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PLK1 | up-regulates 
phosphorylation
|
TRIOBP | 0.34 |
| Publications: | 2 | Organism: | Homo Sapiens | |
| + | GNAQ | up-regulates activity
binding
|
TRIOBP | 0.2 |
| Publications: | 1 | Organism: | In Vitro | |
| + | HECTD3 | down-regulates quantity by destabilization 
polyubiquitination
|
TRIOBP | 0.452 |
| Publications: | 1 | Organism: | Homo Sapiens | |