Summary

Name GNAQ
Full Name Guanine nucleotide-binding protein G
Synonyms Guanine nucleotide-binding protein alpha-q | GAQ
Primary ID P50148
Links - -
Type protein
Relations 106
Pathways Dopaminergic Synapse, Oxytocin signaling, Thyroid Hormone Metabolism
Inhibitors GDP
Function Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity). Transduces FFAR4 signaling in response to long-chain fatty acids (LCFAs).

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding GNAQ 0.592
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding GNAQ 0.2
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.438
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.51
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.561
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.572
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.359
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.44
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding GNAQ 0.524
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.2
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.359
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding GNAQ 0.395
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.325
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding PLCB1 0.759
Publications: 1 Organism: Homo Sapiens
Pathways:Dopaminergic Synapse, Oxytocin signaling, Thyroid Hormone Metabolism
+ up-regulates activity img/direct-activation.png binding GNAQ 0.305
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.504
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png chemical inhibition GNAQ 0.8
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.252
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.349
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.478
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding RHOA 0.594
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.359
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.381
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.409
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.426
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.352
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.359
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.555
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.252
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.2
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding GNAQ 0.45
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.535
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.252
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.57
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.45
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.435
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.403
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.252
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding GNAQ 0.426
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.2
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.413
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.342
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.496
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding GNAQ 0.2
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding GNAQ 0.386
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding PLCE1 0.286
Publications: 1 Organism: Homo Sapiens
Pathways:Oxytocin signaling
+ up-regulates img/direct-activation.png binding GNAQ 0.51
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.523
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.411
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.567
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.533
Publications: 2 Organism: Homo Sapiens
Pathways:Oxytocin signaling
+ up-regulates activity img/direct-activation.png binding GNAQ 0.29
Publications: 1
+ up-regulates activity img/direct-activation.png binding GNAQ 0.461
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding GNAQ 0.629
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.278
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.427
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding GNAQ 0.461
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.64
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.565
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.252
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding TRIOBP 0.2
Publications: 1 Organism: In Vitro
+ up-regulates activity img/direct-activation.png binding GNAQ 0.58
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.44
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.452
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding GNAQ 0.443
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.429
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.478
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding HRAS 0.63
Publications: 1 Organism: Homo Sapiens
Pathways:Oxytocin signaling
+ up-regulates activity img/direct-activation.png binding GNAQ 0.484
Publications: 1 Organism: Homo Sapiens
Pathways:Dopaminergic Synapse
+ up-regulates activity img/direct-activation.png binding GNAQ 0.478
Publications: 1 Organism: Homo Sapiens
Pathways:Dopaminergic Synapse
+ up-regulates activity img/direct-activation.png binding GNAQ 0.551
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.471
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.442
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.304
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.386
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.252
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.41
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.51
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.547
Publications: 1 Organism: Homo Sapiens
Tissue: Thyroid Gland
Pathways:Thyroid Hormone Metabolism
+ up-regulates activity img/direct-activation.png binding GNAQ 0.411
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.443
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.452
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding GNAQ 0.488
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.629
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.411
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.524
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding ARHGEF12 0.429
Publications: 1 Organism: Mus Musculus
+ up-regulates activity img/direct-activation.png binding ARHGEF25 0.569
Publications: 1 Organism: In Vitro
+ up-regulates activity img/direct-activation.png binding GNAQ 0.568
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.599
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.431
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.429
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.497
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.426
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.351
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.471
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.397
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding GNAQ 0.523
Publications: 1 Organism: Homo Sapiens
Tissue: Muscle, Smooth Muscle
+ up-regulates img/direct-activation.png binding GNAQ 0.504
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.427
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.359
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.559
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.443
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding GNAQ 0.469
Publications: 1 Organism: Homo Sapiens
Tissue: Thyroid Gland
Pathways:Thyroid Hormone Metabolism
+ up-regulates activity img/direct-activation.png binding GNAQ 0.278
Publications: 1