3.0
Summary
| Name |  RGCCView Modifications |
| Full Name | Regulator of cell cycle RGCC |
| Synonyms | Response gene to complement 32 protein, RGC-32 | C13orf15, RGC32 |
| Primary ID | Q9H4X1 |
| Links |  -  -  |
| Type | protein |
| Relations | 4 |
| Function | Modulates the activity of cell cycle-specific kinases. Enhances CDK1 activity. May contribute to the regulation of the cell cycle. May inhibit growth of glioma cells by promoting arrest of mitotic progression at the G2/M transition. Fibrogenic factor contributing to the pathogenesis of renal fibrosis through fibroblast activation. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | AKT | up-regulates activity 
phosphorylation
|
RGCC (isoform 2) | 0.2 |
| Publications: | 2 | Organism: | Homo Sapiens | |
| + | CyclinB/CDK1 | up-regulates activity
phosphorylation
|
RGCC | 0.458 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | RGCC | up-regulates activity
binding
|
CDK1 | 0.546 |
| Publications: | 1 | Organism: | Homo Sapiens | |