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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png deacetylation AKT 0.14
Publications: 1 Organism: Mus Musculus
Tissue: Heart
Pathways:AMPK Signaling
+ up-regulates activity img/direct-activation.png sumoylation AKT 0.14
Publications: 1 Organism: Mus Musculus
+ down-regulates quantity by destabilization img/direct_inhibition.png desumoylation AKT 0.14
Publications: 1 Organism: Mus Musculus
+ down-regulates quantity by destabilization img/direct_inhibition.png ubiquitination AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation CDKN1B 0.37
Publications: 3 Organism: Homo Sapiens
Pathways:Cell cycle: G1/S phase transition, Integrin Signalling
+ up-regulates img/direct-activation.png phosphorylation YBX1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation ESR1 0.14
Publications: 4 Organism: Homo Sapiens
Pathways:Luminal Breast Cancer
+ up-regulates img/direct-activation.png phosphorylation H3F3A 0.14
Publications: 1 Organism: Homo Sapiens
+ img/unknown.png phosphorylation PALLD 0.14
Publications: 1 Organism: Homo Sapiens
+ img/unknown.png phosphorylation FANCA 0.14
Publications: 1 Organism: In Vitro
+ up-regulates activity img/direct-activation.png phosphorylation PEA15 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation NOS3 0.2
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation BAD 0.34
Publications: 4 Organism: Homo Sapiens
Pathways:Inhibition of Apoptosis, Malignant Melanoma
+ img/unknown.png phosphorylation RANBP3 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation YAP1 0.14
Publications: 1 Organism: Homo Sapiens
Pathways:Integrin Signalling
+ up-regulates img/direct-activation.png phosphorylation AKT 0.2
Publications: 2 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png phosphorylation CREB1 0.28
Publications: 2 Organism: Homo Sapiens
Pathways:AMPK Signaling, Inhibition of Apoptosis, Malignant Melanoma
+ down-regulates img/direct_inhibition.png phosphorylation NR3C1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation MST1R 0.14
Publications: 1 Organism: Homo Sapiens
+ img/unknown.png phosphorylation CCDC88A 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation ZYX 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation DNMT1 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation MXD1 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation NCOR1 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation, binding CDKN1A 0.2
Publications: 3 Organism: Homo Sapiens
Pathways:Cell cycle: G1/S phase transition, Rhabdomyosarcoma
+ down-regulates img/direct_inhibition.png phosphorylation GAB2 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png phosphorylation MDM2 0.42
Publications: 3 Organism: Homo Sapiens
Tissue: Kidney
Pathways:Acute Myeloid Leukemia, Cell cycle: G1/S phase transition, Luminal Breast Cancer, Malignant Melanoma, Prostate Cancer
+ up-regulates img/direct-activation.png phosphorylation EP300 0.2
Publications: 2 Organism: Homo Sapiens
Tissue: Muscle
+ up-regulates activity img/direct-activation.png phosphorylation BAX 0.14
Publications: 1 Organism: In Vitro
+ down-regulates activity img/direct_inhibition.png phosphorylation BAX 0.14
Publications: 1 Organism: Homo Sapiens
+ img/unknown.png phosphorylation HMOX1 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation KHSRP 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation CASP9 0.2
Publications: 2 Organism: In Vitro, Homo Sapiens
Pathways:Inhibition of Apoptosis
+ down-regulates img/direct_inhibition.png phosphorylation FOXO4 0.23
Publications: 4 Organism: Homo Sapiens
Pathways:Insulin Receptor
+ down-regulates img/direct_inhibition.png phosphorylation, relocalization FOXO 0.33
Publications: 10 Organism: Homo Sapiens, In Vitro, Mus Musculus
Pathways:BCR-ABL in AML, FLT3 in AML, PI3K/AKT
+ down-regulates activity img/direct_inhibition.png phosphorylation FOXO4 0.23
Publications: 2 Organism: Mus Musculus
Pathways:Insulin Receptor
+ down-regulates activity img/direct_inhibition.png phosphorylation FOXO 0.33
Publications: 6 Organism: Mus Musculus, Homo Sapiens
Pathways:BCR-ABL in AML, FLT3 in AML, PI3K/AKT
+ down-regulates img/direct_inhibition.png phosphorylation HNRNPA1 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation EZH2 0.14
Publications: 1 Organism: Homo Sapiens
Pathways:Prostate Cancer
+ down-regulates img/direct_inhibition.png phosphorylation GSK3A 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation HTRA2 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation AR 0.2
Publications: 1 Organism: Homo Sapiens
Pathways:Prostate Cancer
+ up-regulates img/direct-activation.png phosphorylation TERT 0.28
Publications: 2 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation MTOR 0.22
Publications: 1 Organism: Homo Sapiens
Pathways:BCR-ABL in AML, FLT3 in AML, KIT in AML, MTOR Signaling
+ up-regulates img/direct-activation.png phosphorylation TP53RK 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity by destabilization img/direct_inhibition.png phosphorylation FOXO3 0.42
Publications: 3
Pathways:FLT3 in AML, AMPK Signaling, Insulin Receptor, Inhibition of Apoptosis, Integrin Signalling, Thyroid cancer
+ down-regulates activity img/direct_inhibition.png phosphorylation FOXO3 0.42
Publications: 3 Organism: Homo Sapiens
Pathways:FLT3 in AML, AMPK Signaling, Insulin Receptor, Inhibition of Apoptosis, Integrin Signalling, Thyroid cancer
+ down-regulates quantity by destabilization img/direct_inhibition.png phosphorylation FOXO 0.33
Publications: 4 Organism: Homo Sapiens
Pathways:BCR-ABL in AML, FLT3 in AML, PI3K/AKT
+ down-regulates activity img/direct_inhibition.png phosphorylation FOXO1 0.33
Publications: 6 Organism: In Vitro, Homo Sapiens, Mus Musculus
Pathways:FAP: Insulin-mediated adipogenesis, Insulin Receptor, Inhibition of Apoptosis, Rhabdomyosarcoma
+ down-regulates img/direct_inhibition.png phosphorylation RAF1 0.31
Publications: 3 Organism: Homo Sapiens
Tissue: Muscle, Myotube
Pathways:Insulin Receptor, Integrin Signalling
+ img/unknown.png phosphorylation ARFIP2 0.14
Publications: 1 Organism: Homo Sapiens
+ img/unknown.png phosphorylation CCT2 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation METTL1 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity img/direct_inhibition.png phosphorylation CFLAR 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation CHEK1 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation CDKN1C 0.14
Publications: 2 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation PHF20 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation PDE3B 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png phosphorylation PDE3B 0.14
Publications: 2 Organism: Mus Musculus
+ up-regulates img/direct-activation.png phosphorylation NCF1 0.14
Publications: 2 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation SH3RF1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation PIKFYVE 0.14
Publications: 1 Organism: Homo Sapiens
Tissue: Muscle
+ up-regulates img/direct-activation.png phosphorylation GATA1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png phosphorylation BMI1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation CLK2 0.14
Publications: 2 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation ADRB2 0.14
Publications: 2 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation NR4A1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation VCP 0.14
Publications: 3 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation BRAF 0.34
Publications: 3 Organism: Homo Sapiens
Pathways:Acute Myeloid Leukemia, BCR-ABL in AML, FLT3 in AML, KIT in AML, EGFR, Inhibition of Apoptosis, Luminal Breast Cancer, Malignant Melanoma, PI3K/AKT, Rhabdomyosarcoma, RTKs in cancer, Thyroid cancer, T cell activation
+ up-regulates img/direct-activation.png phosphorylation MDM4 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation TTC3 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation VIM 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png phosphorylation MAP3K8 0.14
Publications: 2 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation MAP3K8 0.14
Publications: 2 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation GATA2 0.28
Publications: 1 Organism: Homo Sapiens
Pathways:FAP: Insulin-mediated adipogenesis
+ img/unknown.png phosphorylation HTT 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation TWIST1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation EIF4B 0.14
Publications: 1 Organism: Homo Sapiens
+ img/unknown.png phosphorylation ACLY 0.14
Publications: 1 Organism: Rattus Norvegicus
+ down-regulates img/direct_inhibition.png phosphorylation PDCD4 0.23
Publications: 3 Organism: Homo Sapiens
Tissue: Skin
+ up-regulates img/direct-activation.png phosphorylation PFKFB3 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png phosphorylation PFKFB2 0.23
Publications: 4 Organism: Homo Sapiens
Tissue: Heart
Pathways:AMPK Signaling
+ img/unknown.png phosphorylation PFKFB2 0.14
Publications: 2 Organism: Homo Sapiens
Pathways:AMPK Signaling
+ up-regulates activity img/direct-activation.png phosphorylation AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png phosphorylation AKT 0.38
Publications: 6 Organism: Homo Sapiens, Mus Musculus
Pathways:MTOR Signaling, PI3K/AKT
+ up-regulates img/direct-activation.png phosphorylation AKT 0.28
Publications: 1 Organism: Homo Sapiens
Pathways:Integrin Signalling
+ down-regulates img/direct_inhibition.png dephosphorylation AKT 0.2
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png dephosphorylation AKT 0.2
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png dephosphorylation AKT 0.2
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png dephosphorylation AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png dephosphorylation AKT 0.23
Publications: 3 Organism: Mus Musculus, Homo Sapiens
+ down-regulates img/direct_inhibition.png dephosphorylation AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png dephosphorylation AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation AKT 0.2
Publications: 2 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png phosphorylation AKT 0.2
Publications: 1 Organism: Rattus Norvegicus
+ up-regulates activity img/direct-activation.png phosphorylation AKT 0.2
Publications: 2 Organism: Homo Sapiens
Pathways:BCR-ABL in AML, FLT3 in AML, KIT in AML, MTOR Signaling
+ up-regulates activity img/direct-activation.png phosphorylation AKT 0.28
Publications: 1 Organism: In Vitro
Pathways:Integrin Signalling
+ up-regulates activity img/direct-activation.png phosphorylation AKT 0.14
Publications: 2 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation PTPN1 0.14
Publications: 1 Organism: Mus Musculus
Pathways:Insulin Receptor
+ img/unknown.png phosphorylation CARHSP1 0.14
Publications: 1 Organism: Homo Sapiens
Tissue: Kidney
+ up-regulates img/direct-activation.png phosphorylation CTNNB1 0.31
Publications: 2 Organism: Homo Sapiens
Pathways:Rhabdomyosarcoma, Thyroid cancer
+ img/unknown.png phosphorylation ACAP1 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation PPARGC1A 0.14
Publications: 1 Organism: Homo Sapiens
Tissue: Liver
Pathways:AMPK Signaling, MTOR Signaling
+ img/unknown.png phosphorylation YWHAZ 0.14
Publications: 1 Organism: Homo Sapiens
+ img/unknown.png phosphorylation TBC1D4 0.2
Publications: 2 Organism: Mus Musculus, Homo Sapiens
+ img/unknown.png phosphorylation SH2B2 0.14
Publications: 1 Organism: Mus Musculus
+ up-regulates activity img/direct-activation.png phosphorylation SH2B2 0.14
Publications: 1 Organism: Mus Musculus
+ up-regulates img/direct-activation.png phosphorylation COPS6 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation NUAK1 0.14
Publications: 1 Organism: Homo Sapiens
+ img/unknown.png phosphorylation FAM129A 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png phosphorylation, binding NOS3 0.2
Publications: 2 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation ILF3 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation MAP3K11 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation BRCA1 0.2
Publications: 2 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation RAC1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png phosphorylation TBX3 0.14
Publications: 1 Organism: Homo Sapiens
+ img/unknown.png phosphorylation DLC1 0.14
Publications: 1 Organism: Rattus Norvegicus
+ up-regulates quantity by stabilization img/direct-activation.png phosphorylation ATXN1 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation AR 0.2
Publications: 1 Organism: Chlorocebus Aethiops
Pathways:Prostate Cancer
+ down-regulates img/direct_inhibition.png phosphorylation MAP2K4 0.22
Publications: 1 Organism: Homo Sapiens
Pathways:EGFR
+ down-regulates img/direct_inhibition.png phosphorylation HSPB1 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation MAP3K5 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation BCL2L11 0.14
Publications: 1 Organism: Homo Sapiens
Pathways:Inhibition of Apoptosis
+ up-regulates quantity by stabilization img/direct-activation.png phosphorylation XIAP 0.14
Publications: 1 Organism: Homo Sapiens
Tissue: Ovary Cancer Cell
Pathways:Inhibition of Apoptosis
+ down-regulates activity img/direct_inhibition.png phosphorylation GSK3B 0.37
Publications: 2 Organism: Homo Sapiens
Pathways:Cell cycle: G1/S phase transition, Insulin Receptor, MTOR Signaling, PI3K/AKT
+ down-regulates img/direct_inhibition.png phosphorylation ZFP36L1 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation TSC2 0.14
Publications: 2 Organism: Mus Musculus
+ down-regulates img/direct_inhibition.png phosphorylation RARA 0.14
Publications: 1 Organism: Homo Sapiens
Pathways:Acute Myeloid Leukemia
+ up-regulates img/direct-activation.png phosphorylation AGAP2 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation IRAK1 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation STK3 0.2
Publications: 3 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation STK4 0.2
Publications: 2 Organism: Homo Sapiens
+ down-regulates quantity img/direct_inhibition.png phosphorylation RNF11 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation FOXA2 0.22
Publications: 1 Organism: Homo Sapiens
Pathways:FAP: Insulin-mediated adipogenesis
+ down-regulates img/direct_inhibition.png phosphorylation CDCA7 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation PLN 0.14
Publications: 1 Organism: Mus Musculus
+ up-regulates img/direct-activation.png phosphorylation ALYREF 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation CHUK 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by stabilization img/direct-activation.png phosphorylation POU5F1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png phosphorylation S1PR1 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation AKT1S1 0.14
Publications: 1 Organism: Homo Sapiens
Pathways:MTOR Signaling
+ up-regulates activity img/direct-activation.png phosphorylation AKT 0.49
Publications: 5 Organism: Rattus Norvegicus, Homo Sapiens, Mus Musculus
Tissue: Brain, Muscle, Skeletal Muscle, Myotube
Pathways:Acute Myeloid Leukemia, BCR-ABL in AML, FLT3 in AML, KIT in AML, AMPK Signaling, EGFR, FAP: Insulin-mediated adipogenesis, Insulin Receptor, Luminal Breast Cancer, mTOR in cancer, Malignant Melanoma, MTOR Signaling, Prostate Cancer, PI3K/AKT, Rhabdomyosarcoma, Thyroid cancer, T cell activation
+ up-regulates activity img/direct-activation.png phosphorylation AKT 0.14
Publications: 1
+ down-regulates img/direct_inhibition.png dephosphorylation AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation AKT 0.14
Publications: 1 Organism: Mus Musculus
+ down-regulates img/direct_inhibition.png phosphorylation PPP1CA 0.2
Publications: 2 Organism: Homo Sapiens
Tissue: Brain
+ img/unknown.png phosphorylation LTB4R2 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation CDK2 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png dephosphorylation AKT 0.23
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation SKI 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation SRPK2 0.14
Publications: 1 Organism: Homo Sapiens
Tissue: Brain
+ up-regulates img/direct-activation.png phosphorylation EZR 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation WNK1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png phosphorylation RPS3
Publications: 1 Organism: Rattus Norvegicus
+ down-regulates activity img/direct_inhibition.png phosphorylation ITGB3 0.14
Publications: 1 Organism: In Vitro
Pathways:Integrin Signalling
+ down-regulates img/direct_inhibition.png phosphorylation TAL1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png phosphorylation AKT 0.14
Publications: 1 Organism: Mus Musculus
Tissue: Prostate Adenocarcinoma Cell
+ up-regulates activity img/direct-activation.png phosphorylation AKT 0.2
Publications: 3 Organism: Homo Sapiens, Chlorocebus Aethiops
Pathways:EGFR, Integrin Signalling, Rhabdomyosarcoma
+ up-regulates img/direct-activation.png phosphorylation AKT 0.2
Publications: 2 Organism: Homo Sapiens
Pathways:Thyroid cancer
+ up-regulates img/direct-activation.png phosphorylation AKT 0.2
Publications: 3 Organism: Homo Sapiens
Tissue: Prostate Gland
+ down-regulates img/direct_inhibition.png phosphorylation TBC1D4 0.14
Publications: 1 Organism: Homo Sapiens
Tissue: Muscle
+ down-regulates img/indirect_inhibition.png AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity by repression img/direct_inhibition.png transcriptional regulation AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity by destabilization img/direct_inhibition.png ubiquitination AKT 0.14
Publications: 1 Organism: Mus Musculus
+ up-regulates activity img/indirect-activation.png AKT 0.14
Publications: 1 Organism: Homo Sapiens
Pathways:Acute Myeloid Leukemia, FLT3 in AML
+ down-regulates img/direct_inhibition.png dephosphorylation AKT 0.2
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/indirect_inhibition.png AKT 0.2
Publications: 2 Organism: Homo Sapiens
Pathways:Insulin Receptor, Luminal Breast Cancer, Malignant Melanoma, MTOR Signaling, Prostate Cancer, Thyroid cancer
+ down-regulates img/direct_inhibition.png dephosphorylation AKT 0.14
Publications: 1 Organism: Homo Sapiens
Pathways:Insulin Receptor
+ down-regulates activity img/direct_inhibition.png binding AKT 0.14
Publications: 1 Organism: Homo Sapiens
Tissue: Liver
+ down-regulates quantity by destabilization img/direct_inhibition.png ubiquitination AKT 0.14
Publications: 1 Organism: Mus Musculus
+ down-regulates activity img/direct_inhibition.png phosphorylation PRKAA1 0.14
Publications: 1 Organism: In Vitro
+ up-regulates img/indirect-activation.png MEF2D 0.14
Publications: 1 Organism: Homo Sapiens
Tissue: Muscle, Skeletal Muscle
+ down-regulates activity img/direct_inhibition.png AKT 0.14
Publications: 1 Organism: Homo Sapiens
Pathways:Prostate Cancer
+ down-regulates img/direct_inhibition.png binding CDKN1B 0.37
Publications: 1 Organism: Homo Sapiens
Pathways:Cell cycle: G1/S phase transition, Integrin Signalling
+ up-regulates img/indirect-activation.png Proliferation 0.2
Publications: 2 Organism: Homo Sapiens, Mus Musculus
Pathways:Acute Myeloid Leukemia, BCR-ABL in AML, FLT3 in AML, KIT in AML, EGFR, Integrin Signalling, Luminal Breast Cancer, mTOR in cancer, Malignant Melanoma, Prostate Cancer, Rhabdomyosarcoma, Thyroid cancer
+ up-regulates img/indirect-activation.png AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png dephosphorylation AKT 0.2
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png SLC2A4 0.2
Publications: 2 Organism: Homo Sapiens
Pathways:Insulin Receptor
+ up-regulates img/direct-activation.png phosphorylation SP7 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png dephosphorylation AKT 0.14
Publications: 1 Organism: Mus Musculus
+ down-regulates activity img/direct_inhibition.png binding AKT 0.14
Publications: 1 Organism: Mus Musculus
+ down-regulates img/direct_inhibition.png chemical inhibition AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png binding AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding HK1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png AKT 0.14
Publications: 1 Organism: Homo Sapiens
Tissue: Muscle
+ up-regulates img/direct-activation.png binding AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png dephosphorylation AKT 0.2
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png AKT 0.14
Publications: 1 Organism: Mus Musculus
Pathways:AMPK Signaling, FAP: Insulin-mediated adipogenesis, Insulin Receptor, mTOR in cancer, MTOR Signaling
+ up-regulates activity img/indirect-activation.png phosphorylation AKT 0.2
Publications: 1 Organism: Mus Musculus
+ up-regulates img/direct-activation.png relocalization AKT 0.45
Publications: 1 Organism: Rattus Norvegicus
+ down-regulates img/direct_inhibition.png phosphorylation FOXA2 0.22
Publications: 1 Organism: Homo Sapiens
Pathways:FAP: Insulin-mediated adipogenesis
+ up-regulates img/direct-activation.png phosphorylation DLX5 0.2
Publications: 2 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png phosphorylation mTORC1 0.37
Publications: 2 Organism: Mus Musculus, Homo Sapiens
Tissue: Muscle, Skeletal Muscle, Myotube
Pathways:AMPK Signaling, Insulin Receptor, Luminal Breast Cancer, PI3K/AKT
+ up-regulates img/indirect-activation.png MTOR 0.22
Publications: 1 Organism: Homo Sapiens
Tissue: Muscle, Skeletal Muscle
Pathways:BCR-ABL in AML, FLT3 in AML, KIT in AML, MTOR Signaling
+ up-regulates img/direct-activation.png binding AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation GSK3B 0.37
Publications: 1
Pathways:Cell cycle: G1/S phase transition, Insulin Receptor, MTOR Signaling, PI3K/AKT
+ down-regulates img/direct_inhibition.png dephosphorylation AKT 0.2
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation IKK-complex 0.28
Publications: 1 Organism: Homo Sapiens
Pathways:Acute Myeloid Leukemia, Inhibition of Apoptosis, T cell activation
+ down-regulates activity img/indirect_inhibition.png AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png dephosphorylation AKT 0.14
Publications: 1 Organism: Mus Musculus
+ up-regulates activity img/indirect-activation.png AKT 0.14
Publications: 1 Organism: Mus Musculus
Pathways:Rhabdomyosarcoma
+ down-regulates activity img/direct_inhibition.png phosphorylation TSC1/TSC2 0.31
Publications: 1 Organism: Mus Musculus
Pathways:AMPK Signaling, Insulin Receptor, Luminal Breast Cancer, mTOR in cancer, MTOR Signaling
+ up-regulates activity img/indirect-activation.png AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png binding AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/indirect_inhibition.png AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/indirect-activation.png phosphorylation ELK1 0.22
Publications: 1 Organism: Homo Sapiens
Pathways:EGFR, Integrin Signalling
+ down-regulates img/direct_inhibition.png chemical inhibition AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png chemical inhibition AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png relocalization AKT 0.45
Publications: 1 Organism: Homo Sapiens
Tissue: Prostate Gland Cancer Cell
+ down-regulates img/direct_inhibition.png phosphorylation FOXO6 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png binding PHB2 0.14
Publications: 1 Organism: Mus Musculus
+ down-regulates img/direct_inhibition.png relocalization FOXO1 0.33
Publications: 1 Organism: Mus Musculus
Pathways:FAP: Insulin-mediated adipogenesis, Insulin Receptor, Inhibition of Apoptosis, Rhabdomyosarcoma
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation CTNNB1 0.31
Publications: 1 Organism: Homo Sapiens
Pathways:Rhabdomyosarcoma, Thyroid cancer
+ down-regulates activity img/direct_inhibition.png cleavage AKT 0.14
Publications: 1 Organism: In Vitro
+ down-regulates activity img/indirect_inhibition.png AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation SLC2A1 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/indirect_inhibition.png AKT 0.28
Publications: 1 Organism: Homo Sapiens
Tissue: Muscle
Pathways:Cell cycle: G1/S phase transition
+ up-regulates activity img/indirect-activation.png AKT 0.28
Publications: 1 Organism: Homo Sapiens
Pathways:Cell cycle: G1/S phase transition, RTKs in cancer
+ down-regulates img/indirect_inhibition.png AKT 0.14
Publications: 1
+ up-regulates activity img/indirect-activation.png AKT 0.4
Publications: 2 Organism: Homo Sapiens
Tissue: Breast Cancer Cell
Pathways:BCR-ABL in AML, FLT3 in AML, KIT in AML, FAP: Insulin-mediated adipogenesis, Integrin Signalling, mTOR in cancer, PI3K/AKT, RTKs in cancer
+ up-regulates img/indirect-activation.png AKT 0.14
Publications: 1 Organism: Homo Sapiens
Pathways:Inhibition of Apoptosis
+ down-regulates activity img/direct_inhibition.png dephosphorylation AKT 0.2
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/indirect_inhibition.png MAPK14 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/indirect-activation.png AKT 0.28
Publications: 1 Organism: Homo Sapiens
Tissue: Breast Cancer Cell
Pathways:Acute Myeloid Leukemia, AMPK Signaling, EGFR, Luminal Breast Cancer, mTOR in cancer, Malignant Melanoma, MTOR Signaling, Prostate Cancer, Rhabdomyosarcoma
+ up-regulates img/direct-activation.png relocalization AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png cleavage AKT 0.14
Publications: 1 Organism: In Vitro
Pathways:Inhibition of Apoptosis
+ up-regulates img/indirect-activation.png Survival 0.42
Publications: 2 Organism: Homo Sapiens
Pathways:Inhibition of Apoptosis, Luminal Breast Cancer, Malignant Melanoma, Prostate Cancer, Rhabdomyosarcoma, Thyroid cancer
+ down-regulates img/direct_inhibition.png binding SMAD3 0.14
Publications: 1 Organism: Homo Sapiens
Pathways:Cell cycle: G1/S phase transition, Thyroid cancer
+ down-regulates img/indirect_inhibition.png FAS 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/indirect_inhibition.png AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png chemical inhibition AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/indirect_inhibition.png AKT 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/indirect_inhibition.png INSIG2 0.14
Publications: 1 Organism: Mus Musculus
Tissue: Liver
+ up-regulates activity img/direct-activation.png phosphorylation AKT 0.4
Publications: 1 Organism: Homo Sapiens
Pathways:BCR-ABL in AML, FLT3 in AML, KIT in AML, FAP: Insulin-mediated adipogenesis, Integrin Signalling, mTOR in cancer, PI3K/AKT, RTKs in cancer
+ up-regulates img/indirect-activation.png PRKACA 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/indirect-activation.png relocalization AKT 0.45
Publications: 1 Organism: Homo Sapiens
Tissue: Breast Cancer Cell
+ up-regulates img/direct-activation.png binding AKT 0.22
Publications: 1 Organism: Homo Sapiens
Pathways:Acute Myeloid Leukemia, FLT3 in AML
+ up-regulates activity img/direct-activation.png phosphorylation AKT 0.28
Publications: 1 Organism: Homo Sapiens
Pathways:Acute Myeloid Leukemia, AMPK Signaling, EGFR, Luminal Breast Cancer, mTOR in cancer, Malignant Melanoma, MTOR Signaling, Prostate Cancer, Rhabdomyosarcoma