Name	KAT8
Full Name	Histone acetyltransferase KAT8
Synonyms	Lysine acetyltransferase 8, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1, MYST-1, hMOF \| MOF, MYST1
Primary ID	Q9H7Z6
Links	- -
Type	protein
Relations	4
Function	Histone acetyltransferase which may be involved in transcriptional activation (PubMed:12397079, PubMed:22020126). May influence the function of ATM (PubMed:15923642). As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac (PubMed:16227571, PubMed:16543150, PubMed:21217699, PubMed:22547026, PubMed:22020126). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (PubMed:20018852, PubMed:22547026). That activity is less specific than the one of the MSL complex (PubMed:20018852, PubMed:22547026). Can also acetylate TP53/p53 at 'Lys-120'.