| + |
IL21R | up-regulates 
|
STAT3 |
0.613 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-133379 |
|
|
Homo sapiens |
Monocyte |
| pmid |
sentence |
| 15667561 |
Interleukin 24 (il-24) is a new member of the il-10 family of cytokines and it signals through two heterodimeric receptors: il-20r1/il-20r2 and il-22r1/il-20r2. Upon binding to its receptors, il-24 induces rapid activation of stat-1 and stat-3 transcription factors, |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Lung, Skin |
| + |
IL21R | up-regulates 
binding
|
JAK1 |
0.629 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-90266 |
|
|
Homo sapiens |
B-lymphocyte |
| pmid |
sentence |
| 12093291 |
Retroviral-mediated transduction of wild-type gamma c into xscid jt cells restored function to the il-21r, as shown by il-21-induced tyrosine phosphorylation of jak1 and jak3, and downstream activation of stat5 |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
IL21 | up-regulates
binding
|
IL21R |
0.901 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-143849 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 16424177 |
Il-21 mediates its biological effects via the il-21r in conjunction with the common receptor gamma-chain that is also shared by members of the il-2 family |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
IL21R | up-regulates
binding
|
JAK3 |
0.562 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-90269 |
|
|
Homo sapiens |
B-lymphocyte |
| pmid |
sentence |
| 12093291 |
Retroviral-mediated transduction of wild-type gamma c into xscid jt cells restored function to the il-21r, as shown by il-21-induced tyrosine phosphorylation of jak1 and jak3, and downstream activation of stat5 |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
IL21R
- 
- 