+ |
MOV10 | up-regulates activity
binding
|
IKBKE |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-261138 |
|
|
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
27016603 |
MOV10 enhances IRF3 activation and IRF3-mediated gene induction. This indicated that MOV10-mediated antiviral activity is most likely mediated through IKKε and not through TBK1. Involvement of IKKε was further established by examining the physical interaction of MOV10 and IKKε. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
Interferon-type-I | up-regulates quantity by expression
transcriptional regulation
|
MOV10 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-261137 |
|
|
Homo sapiens |
|
pmid |
sentence |
32496609 |
Mov10 is a processing body (P-body) protein and an interferon-stimulated gene that can affect replication of retroviruses, hepatitis B virus, and hepatitis C virus (HCV). |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
MOV10 | up-regulates activity
binding
|
UPF1 |
0.535 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-261139 |
|
|
Homo sapiens |
|
pmid |
sentence |
27016603 |
MOV10 has been shown to promote mRNA degradation by associating with UPF1, this activity requires the helicase activity of MOV10. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |