Bithoraxoid-like protein, BLP, Dynein light chain 2A, cytoplasmic, Dynein-associated protein Km23, Roadblock domain-containing protein 1 | BITH, DNCL2A, DNLC2A, ROBLD1
Primary ID
Q9NP97
Links
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Type
protein
Relations
1
Function
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
Our results show that km23-1 is required for camp-responsive element (cre) transcriptional activation by tgf_, with s73-km23-1 being required for the cre-dependent tgf_ stimulation of fibronectin (fn) transcription.