3.0
Summary
| Name |  ASH1LView Modifications |
| Full Name | Histone-lysine N-methyltransferase ASH1L |
| Synonyms | ASH1-like protein, huASH1, Absent small and homeotic disks protein 1 homolog, Lysine N-methyltransferase 2H | KIAA1420, KMT2H |
| Primary ID | Q9NR48 |
| Links |  -  -  |
| Type | protein |
| Relations | 4 |
| Function | Histone methyltransferase specifically trimethylating 'Lys-36' of histone H3 forming H3K36me3 (PubMed:21239497). Also monomethylates 'Lys-9' of histone H3 (H3K9me1) in vitro (By similarity). The physiological significance of the H3K9me1 activity is unclear (By similarity). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | ASH1L | up-regulates activity 
trimethylation
|
H3C1 | 0.2 |
| Publications: | 1 | Organism: | In Vitro | |
| + | ASH1L | up-regulates quantity by expression
transcriptional regulation
|
NTRK2 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | NEUROG3 | down-regulates quantity by repression 
transcriptional regulation
|
ASH1L | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | ASH1L | down-regulates quantity by repression 
transcriptional regulation
|
NRXN1 | 0.262 |
| Publications: | 1 | Organism: | Homo Sapiens | |