Relation Results

Summary

Name ELOVL2
Full Name Elongation of very long chain fatty acids protein 2
Synonyms 3-keto acyl-CoA synthase ELOVL2, ELOVL fatty acid elongase 2, ELOVL FA elongase 2, Very long chain 3-ketoacyl-CoA synthase 2, Very long chain 3-oxoacyl-CoA synthase 2 | SSC2
Primary ID Q9NXB9
Links - -
Type protein
Relations 2
Function Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic ret ...
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Type: Score: Layout: SPV 
0.80.8ELOVL2palmitoyl-CoA3-hydroxyoctadecanoyl-CoA

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Relations
Regulator
Mechanism
target
score ℹ
+ ELOVL2down-regulates quantity img/direct_inhibition.png chemical modification palmitoyl-CoA 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-267890 Homo sapiens
pmid sentence
The ELOVL family of enzymes in mammals is comprised of seven members that all reside in the endoplasmic reticulum (ER) and are thought to form a multimeric complex. Together, the ELOVL family is responsible for the elongation of saturated and unsaturated fatty acids.Fatty acid elongation occurs by cycling through a four step process (condensation, reduction, dehydration, and reduction), with two carbon atoms added through each cycle.
Publications: 1 Organism: Homo Sapiens
+ ELOVL2up-regulates quantity img/direct-activation.png chemical modification 3-hydroxyoctadecanoyl-CoA 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-267897 Homo sapiens
pmid sentence
The ELOVL family of enzymes in mammals is comprised of seven members that all reside in the endoplasmic reticulum (ER) and are thought to form a multimeric complex. Together, the ELOVL family is responsible for the elongation of saturated and unsaturated fatty acids.Fatty acid elongation occurs by cycling through a four step process (condensation, reduction, dehydration, and reduction), with two carbon atoms added through each cycle.
Publications: 1 Organism: Homo Sapiens
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