Summary

Name MAT2B
Full Name Methionine adenosyltransferase 2 subunit beta
Synonyms Methionine adenosyltransferase II beta, MAT II beta, Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase | TGR
Primary ID Q9NZL9
Links - -
Type protein
Relations 4
Function Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine (PubMed:10644686, PubMed:23189196, PubMed:25075345). Can bind NADP (in vitro) (PubMed:23189196, PubMed:23425511).

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding GIT1 0.409
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/indirect_inhibition.png Apoptosis 0.7
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png Proliferation 0.7
Publications: 2 Organism: Homo Sapiens