Relation Results

Summary

Name CALCOCO1
Full Name Calcium-binding and coiled-coil domain-containing protein 1
Synonyms Calphoglin, Coiled-coil coactivator protein, Sarcoma antigen NY-SAR-3 | KIAA1536
Primary ID Q9P1Z2
Links - -
Type protein
Relations 2
Function Functions as a coactivator for aryl hydrocarbon and nuclear receptors (NR). Recruited to promoters through its contact with the N-terminal basic helix ...
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Type: Score: Layout: SPV 
0.20.2TFEBCALCOCO1SMURF1

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Relations
Regulator
Mechanism
target
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+ TFEBup-regulates quantity by expression img/indirect-activation.png transcriptional regulation CALCOCO1 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-276784
pmid sentence
Among the differentially expressed genes, we detected upregulation of known targets in TFEB-WT and TFEB-nuc cells (Figure 2B; Tables S1 and S2), including genes functioning in lysosomal and autophagy pathways|Using quantitative PCR (qPCR), we validated expression patterns observed by RNA sequencing for selected genes (CTSD, SQSTM1, MCOLN1, IL33, FAP, GPNMB, IFI30, FOLR1, and G0S2)
Publications: 1
+ SMURF1 img/unknown.png ubiquitination CALCOCO1 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-272688 in vitro
pmid sentence
Recombinant proteins were used to profile substrate ubiquitination by the Smurf1 ubiquitin ligase on a global scale using protein microarrays. T Proteins ubiquitinated on the protein microarray were confirmed as potential substrates of the Smurf1 activity using an off chip in vitro ubiquitination assay.
Publications: 1 Organism: In Vitro
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