3.0
Summary
| Name |  KLHL13
|
| Full Name | Kelch-like protein 13 |
| Synonyms | BTB and kelch domain-containing protein 2 | BKLHD2, KIAA1309 |
| Primary ID | Q9P2N7 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis. {ECO:0000269|PubMed:14528312, ECO:0000269|PubMed:17543862, ECO:0000269|PubMed:19995937}. |
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