+ |
RERE | up-regulates activity
relocalization
|
BAX |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-264485 |
|
|
Homo sapiens |
Neuroblastoma Cell Line |
pmid |
sentence |
11331249 |
We detected RERE protein mainly in the nucleus, where it colocalizes with the promyelocytic leukemia protein in promyelocytic leukemia oncogenic domains (PODs). Overexpression of RERE recruits a fraction of the proapoptotic protein BAX to PODS: This observation correlates with RERE-induced apoptosis, which occurs in a caspase-dependent manner. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
RERE | up-regulates activity
binding
|
NOTCH1 |
0.324 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-264486 |
|
|
Homo sapiens |
Neuroblastoma Cell Line |
pmid |
sentence |
28144959 |
In mammalian cells, RERE co‐immunoprecipitates with CBF1 and Notch intracellular domain (NICD), and is recruited to nuclear foci formed by over‐expressed NICD1. RERE is also necessary for NICD to activate the expression of Notch target genes. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |