3.0
Summary
| Name |  MAGEC2
|
| Full Name | Melanoma-associated antigen C2 |
| Synonyms | Cancer/testis antigen 10, CT10, Hepatocellular carcinoma-associated antigen 587, MAGE-C2 antigen, MAGE-E1 antigen | HCA587, MAGEE1 |
| Primary ID | Q9UBF1 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex. |
binding