Relation Results

Summary

Name NXF1
Full Name Nuclear RNA export factor 1
Synonyms Tip-associated protein, Tip-associating protein, mRNA export factor TAP | TAP
Primary ID Q9UBU9
Links - -
Type protein
Relations 6
Function Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to ...
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Type: Score: Layout: SPV 
0.70.6560.5020.3050.6670.361NXF1mRNA-nucleus_exportSRSF7RBM15/NXF1LINC complexSRSF3SUN1

Relations

Regulator
Mechanism
target
score
+ up-regulates img/indirect-activation.png mRNA-nucleus_export 0.7
Identifier Residue Sequence Organism Cell Line
SIGNOR-263298 Homo sapiens
pmid sentence
SUN1, a component of the LINC (Linker of Nucleoskeleton and Cytoskeleton) complex, functions in mammalian mRNA export through the NXF1-dependent pathway. It associates with mRNP complexes by direct interaction with NXF1.
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding NXF1 0.656
Identifier Residue Sequence Organism Cell Line
SIGNOR-161338 Homo sapiens
pmid sentence
9g8 and srp20 also enhance the tap rna-binding activity
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding RBM15/NXF1 0.502
Identifier Residue Sequence Organism Cell Line
SIGNOR-149880 Homo sapiens
pmid sentence
Rbm15 binds to nxf1 and the two proteins cooperate in stimulating rte-mediated mrna export and expression.
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding NXF1 0.305
Identifier Residue Sequence Organism Cell Line
SIGNOR-263297 Homo sapiens HeLa Cell
pmid sentence
SUN1, a component of the LINC (Linker of Nucleoskeleton and Cytoskeleton) complex, functions in mammalian mRNA export through the NXF1-dependent pathway. It associates with mRNP complexes by direct interaction with NXF1.
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding NXF1 0.667
Identifier Residue Sequence Organism Cell Line
SIGNOR-178111 Homo sapiens
pmid sentence
9g8 and srp20 also enhance the tap rna-binding activity
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding NXF1 0.361
Identifier Residue Sequence Organism Cell Line
SIGNOR-263296 Homo sapiens HeLa Cell
pmid sentence
SUN1, a component of the LINC (Linker of Nucleoskeleton and Cytoskeleton) complex, functions in mammalian mRNA export through the NXF1-dependent pathway. It associates with mRNP complexes by direct interaction with NXF1.
Publications: 1 Organism: Homo Sapiens
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