+ |
APC-c | down-regulates quantity by destabilization
polyubiquitination
|
REV1 |
0.342 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-272895 |
|
|
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
23287467 |
Here, we show that human REV1 undergoes proteosomal degradation mediated by the E3 ubiquitin ligase known as anaphase-promoting complex (APC). REV1 associates with APC. Overexpression of APC coactivator CDH1 or CDC20 promotes polyubiquitination and proteosomal degradation of REV1. |
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-272894 |
|
|
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
23287467 |
Here, we show that human REV1 undergoes proteosomal degradation mediated by the E3 ubiquitin ligase known as anaphase-promoting complex (APC). REV1 associates with APC. Overexpression of APC coactivator CDH1 or CDC20 promotes polyubiquitination and proteosomal degradation of REV1. |
|
Publications: |
2 |
Organism: |
Homo Sapiens |
+ |
CDC20 | down-regulates quantity by destabilization
binding
|
REV1 |
0.277 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-272892 |
|
|
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
23287467 |
Here, we show that human REV1 undergoes proteosomal degradation mediated by the E3 ubiquitin ligase known as anaphase-promoting complex (APC). REV1 associates with APC. Overexpression of APC coactivator CDH1 or CDC20 promotes polyubiquitination and proteosomal degradation of REV1. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
FZR1 | down-regulates quantity by destabilization
binding
|
REV1 |
0.243 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-272893 |
|
|
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
23287467 |
Here, we show that human REV1 undergoes proteosomal degradation mediated by the E3 ubiquitin ligase known as anaphase-promoting complex (APC). REV1 associates with APC. Overexpression of APC coactivator CDH1 or CDC20 promotes polyubiquitination and proteosomal degradation of REV1. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |