Summary

Name REV1
Full Name DNA repair protein REV1
Synonyms EC 2.7.7.-, Alpha integrin-binding protein 80, AIBP80, Rev1-like terminal deoxycytidyl transferase | REV1L
Primary ID Q9UBZ9
Links - -
Type protein
Relations 4
Function Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents. {ECO:0000269|PubMed:10536157, ECO:0000269|PubMed:10760286, ECO:0000269|PubMed:11278384, ECO:0000269|PubMed:11485998, ECO:0000269|PubMed:22266823}.

Viewer

Relations

Regulator Mechanism target score
+ down-regulates quantity by destabilization img/direct_inhibition.png polyubiquitination REV1 0.342
Publications: 2 Organism: Homo Sapiens
+ down-regulates quantity by destabilization img/direct_inhibition.png binding REV1 0.277
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity by destabilization img/direct_inhibition.png binding REV1 0.243
Publications: 1 Organism: Homo Sapiens