Name	MALT1
Full Name	Mucosa-associated lymphoid tissue lymphoma translocation protein 1
Synonyms	MALT lymphoma-associated translocation, Paracaspase \| MLT
Primary ID	Q9UDY8
Links	- -
Type	protein
Relations	5
Function	Protease that enhances BCL10-induced activation of NF-kappa-B by mediating its cleavage (PubMed:11262391, PubMed:18264101). MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion (PubMed:11262391, PubMed:18264101). Involved in the induction of T helper 17 cells (Th17) differentiation (PubMed:11262391, PubMed:18264101). Cleaves RC3H1 and ZC3H12A in response to T-cell receptor (TCR) stimulation which releases their cooperatively repressed targets to promote Th17 cell differentiation (By similarity). Also mediates cleavage of N4BP1 in T-cells following TCR-mediated activation, leading to N4BP1 inactivation (PubMed:31133753). Also has ubiquitin ligase activity