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Summary
Name
SEPTIN9
Full Name
Septin-9
Synonyms
MLL septin-like fusion protein MSF-A, MLL septin-like fusion protein, Ovarian/Breast septin, Ov/Br septin, Septin D1 | KIAA0991, MSF
Primary ID
Q9UHD8
Links
-
-
Type
protein
Relations
2
Function
Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.
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by mechanism
none
binding
unknown
by effect
none
down-regulates
by organism:
none
Homo sapiens
by tissue:
none
by cell-line
none
Relations
Regulator
Mechanism
target
score
ℹ
+
SEPTIN9
down-regulates
binding
ARHGEF18
0.2
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-131184
Homo sapiens
pmid
sentence
15558029
In transient expression analyses, sept9b inhibited sa-rhogef-dependent rho activation in cos7 and hela cells.
Publications:
1
Organism:
Homo Sapiens
+
RTKN
down-regulates
SEPTIN9
0.2
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-138578
Homo sapiens
pmid
sentence
16007136
We identified rhotekin, a downstream effector for rho, as a candidate regulator organizing septin structures through filament disruption.
Publications:
1
Organism:
Homo Sapiens