Summary

Name TRPS1
Full Name Zinc finger transcription factor Trps1
Synonyms Tricho-rhino-phalangeal syndrome type I protein, Zinc finger protein GC79 |
Primary ID Q9UHF7
Links - -
Type protein
Relations 2
Function Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes.

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Relations

Regulator Mechanism target score
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation GDF5 0.311
Publications: 1 Organism: Mus Musculus
+ up-regulates activity img/direct-activation.png relocalization TRPS1 0.311
Publications: 1 Organism: Mus Musculus