3.0
Summary
| Name |  SLC24A2View Modifications |
| Full Name | Sodium/potassium/calcium exchanger 2 |
| Synonyms | Na(+)/K(+)/Ca(2+)-exchange protein 2, Retinal cone Na-Ca+K exchanger, Solute carrier family 24 member 2 | NCKX2 |
| Primary ID | Q9UI40 |
| Links |  -  -  |
| Type | protein |
| Relations | 5 |
| Function | Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). |
Viewer
Search Tools
Refine search:
- by mechanism
- by effect
- by organism:
- by tissue:
- by cell-line
Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | SRC_kinase_family | up-regulates quantity 
phosphorylation
|
SLC24A2 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | SLC24A2 | up-regulates quantity
relocalization
|
sodium(1+) | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | SLC24A2 | down-regulates quantity 
relocalization
|
potassium(1+) | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | AP2M1 | down-regulates quantity
binding
|
SLC24A2 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | SLC24A2 | down-regulates quantity
relocalization
|
calcium(2+) | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |