+ |
MUTYH | up-regulates
|
Base-excision_repair |
0.7 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-275716 |
|
|
|
|
pmid |
sentence |
23545420 |
The BER pathway is initiated by one of at least 11 distinct DNA glycosylases, depending on the type of lesion (Table 1). |
|
Publications: |
1 |
+ |
MUTYH | up-regulates
|
CHEK1 |
0.349 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-173969 |
|
|
Homo sapiens |
|
pmid |
sentence |
21615992 |
Hmyh is involved in the activation mechanism of chk1 upon dna damage, but not in stability or inactivation. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
MUTYH | up-regulates
binding
|
TOPBP1 |
0.382 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-173972 |
|
|
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
21615992 |
Binding of myh directly participates in atr and topbp1 activation in dna damage signaling, leading to apoptosis. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
MUTYH | up-regulates
binding
|
ATR |
0.252 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-173966 |
|
|
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
21615992 |
Binding of myh directly participates in atr and topbp1 activation in dna damage signaling, leading to apoptosis. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |