Summary

Name HOOK1
Full Name Protein Hook homolog 1
Synonyms h-hook1, hHK1 |
Primary ID Q9UJC3
Links - -
Type protein
Relations 2
Function Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex) (PubMed:18799622).

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Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png binding PTPN11 0.362
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/indirect_inhibition.png Epithelial-mesenchymal_transition 0.7
Publications: 1 Organism: Homo Sapiens