Relation Results

Name	KLHL21
Full Name	Kelch-like protein 21
Synonyms	\| KIAA0469
Primary ID	Q9UJP4
Links	- -
Type	protein
Relations	3
Function	Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome. {ECO:0000269\|PubMed:14528312, ECO:0000269\|PubMed:19995937}.