Summary

Name APPL1
Full Name DCC-interacting protein 13-alpha
Synonyms Dip13-alpha, Adapter protein containing PH domain, PTB domain and leucine zipper motif 1 | APPL, DIP13A, KIAA1428
Primary ID Q9UKG1
Links - -
Type protein
Relations 3
Function Adapter protein that interacts with proteins involved in different cellular signaling pathways. Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction. Involved in the regulation of the insulin receptor signaling pathway.

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding APPL1 0.34
Publications: 1 Organism: Homo Sapiens
Tissue: Brain
+ up-regulates img/direct-activation.png binding APPL1 0.22
Publications: 1 Organism: Homo Sapiens
Tissue: Brain
+ up-regulates img/direct-activation.png binding STK11 0.14
Publications: 1 Organism: Homo Sapiens
Tissue: Muscle